Transcatheter closure of perimembranous ventricular septal defect with muscular VSD occluder after infective endocarditis in a patient with previous primum atrial septal defect closure, prosthetic aortic and mitral valves replacement. (RCD code IV‑2B.3)

Agnieszka Sarnecka, Piotr Weryński, Piotr Wilkołek, Lidia Tomkiewicz‑Pająk, Mateusz Brózda, Piotr Podolec

Full Text:



Ventricular septal defect (VSD) is the most common congenital heart defect at birth but is relatively rare in adult population. Apart from congenital, VSD may also be acquired. It can be caused by trauma, myocardial infarction or previous cardiac surgeries such as valvular replacements or VSD closure attempts. Surgical closure of VSD remains the treatment of choice while transcatheter closure could be considered in selected patients. Herein, we present a case of a 53-year-old man with symptomatic perimembranous VSD after infective endocarditis and a history of previous primum atrial septal defect closure and prosthetic aortic and mitral valves replacement. The VSD was successfully percutaneously closed across the prosthetic aortic valve. JRCD 2017; 3 (2): 59–64


rare cardiovascular disease; acquired ventricular septal defect; transcatheter intervention


Baumgartner H, Bonhoeffer P, De Groot NMS, et al. ESC Guidelines for the management of grown‑up congenital heart disease (new version 2010): The Task Force on the Management of Grown‑up Congenital Heart Disease of the European Society of Cardiology (ESC). Eur Heart J 2010; 31: 2915–2957.

Warnes CA, Williams RG, Bashore TM, et al. ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease. J Am Coll Cardiol 2008; 52: 1890–1947.

Pineda AM, Mihos CG, Singla S, et al. Percutaneous Closure of Intracardiac Defects in Adults: State of the Art. J Invasive Cardiol 2015; 27: 561–572.

Ashmeik K, Pai RG. An unusual case of acquired ventricular septal defect as a complication of aortic valve endocarditis: echocardiographic delineation of multiple subvalvular complications in one patient. J Am Soc Echocardiogr 2000; 13: 693–695.

Lock JE, Block PC, McKay RG, et al. Transcatheter closure of ventricular septal defects. Circulation 1988; 78: 361–368.

Zheng Q, Zhao Z, Zuo J, et al. A comparative study: Early results and complications of percutaneous and surgical closure of ventricular septal defect. Cardiology 2009; 114: 238–243.

Butera G, Carminati M, Chessa M, et al. Transcatheter Closure of Perimembranous Ventricular Septal Defects. Early and Long‑Term Results. J Am Coll Cardiol 2007; 50: 1189–1195.

Tzikas A, Ibrahim R, Velasco‑Sanchez D, et al. Transcatheter closure of perimembranous ventricular septal defect with the Amplatzer membranous VSD occluder 2: Initial world experience and one‑year follow‑up. Catheter Cardiovasc Interv 2014; 83: 571–580.

Szkutnik M, Qureshi SA, Kusa J, et al. Use of the Amplatzer muscular ventricular septal defect occluder for closure of perimembranous ventricular septal defects. Heart 2007; 93: 355–358.

Kober G, Hilgermann R. Catheter entrapment in a Björk-Shiley prosthesis in aortic position. Cathet Cardiovasc Diagn 1987; 13: 262–265.

Horstkotte D, Jehle J, Loogen F. Death due to transprosthetic catheterization of a Björk‑Shiley prosthesis in the aortic position. Am J Cardiol 1986; 58: 566–567.

Holzer R, Latson L, Hijazi ZM. Device closure of iatrogenic membranous ventricular septal defects after prosthetic aortic valve replacement using the amplatzer membranous ventricular septal defect occluder. Catheter Cardiovasc Interv 2004; 62: 276–280.

Noble S, Ibrahim R. Transcatheter membranous ventricular septal defect closure through a mechanical aortic prosthesis using the amplatzer membranous ventricular septal defect occluder. Catheter Cardiovasc Interv 2009; 73: 167–172.

Chojnicki M, Sukiennik A, Anisimowicz L, et al. Transcatheter closure of iatrogenic perimembranous ventricular septal defect after aortic valve and ascending aorta replacement using an Amplatzer membranous ventricular septal occluder. Cardiol J 2008; 15: 189–191.

Goy J‑J, Ruchat P, Stolt V, et al. Percutaneous closure of ventricular septal defect following aortic valve replacement. Kardiovaskulare Medizin 2014; 17: 266–268.



  • There are currently no refbacks.
Journal of Rare Cardiovascular Diseases (JRCD)
John Paul II Hospital in Kraków, 80 Prądnicka Str., 31-202 Kraków, Poland
Phone: +48 (12) 614 33 99, +48 (12) 614 34 88 Fax: +48 (12) 614 34 88
Published by SoftQ sp. z o.o.
ul. Oleandry 2, 30-063 Kraków, Poland
Phone: +48 (12) 444 1650 Fax: +48 (12) 444 1659