Journal of Rare Cardiovascular Diseases

ISSN: 2299-3711 (Print) | e-ISSN: 2300-5505 (Online)

Correlation between the posterior left ventricular wall thickness and relative wall thickness with global longitudinal strain (gls) in women with preeclampsia

Manal Yahya I. AL-Muhana1, Amina A. B. AL-Dujeli2
1Karbala Health Department Iraq
2Facility of Medicine, University of Kufa, Iraq
Manal Yahya I. AL-Muhana1, Amina A. B. AL-Dujeli2
1Karbala Health Department Iraq
2Facility of Medicine, University of Kufa, Iraq
Corresponding Email: dr.manalzim1977@gmail.com
  • Received 01/10/2024
  • Revised 30/10/2024
  • Accepted 01/01/2025
  • Published 24/02/2025

Full Text:

PDF
Abstract

Background: Pregnancy outcomes for mothers, fetuses, and newborns are impacted by hypertensive diseases, which affect 5–10% of pregnancies. One of the main causes of pregnancy-related morbidity and mortality is hypertensive disorders of pregnancy (HDP). The effects of these diseases are extensive and go much beyond conception and the first few months after giving birth. According to the American Congress of Obstetricians and Gynecologists’ (ACOG) standards, hypertensive disorders during pregnancy can be divided into four categories: gestational hypertension, preeclampsia, chronic hypertension, and chronic hypertension with preeclampsia superimposed [1]. High blood pressure and protein in the urine are signs of preeclampsia, which develops after week 20 of pregnancy. A condition known as preeclampsia can endanger the lives of both the mother and the fetus during pregnancy. Studies have demonstrated how preeclampsia directly affects several cardiac functioning indices as well as left ventricular mass (LV mass). Aim of study: This study aims to evaluate the correlation between posterior wall thickness (PWT) of LV and relative wall thickness (RWT) with global longitudinal strain (GLS%) in preeclampsia by conventional and advanced echocardiographic modalities. Method: A cross sectional study of total number 50 pregnant ladies with preeclampsia Our study reported from 2023 to 2024, at AL-Hussain teaching hospital. Two-D conventional echocardiography, Tissue Doppler Imaging and Global longitudinal strain (GLS%) by speckle-tracking echocardiography had been performed. Statistical data analysis of correlation was done and the significance value was <0.05). Results: There is a significant correlation between the GLS% and PWT among preeclamptic women. (N=50, r=0.7, p=0.0001) as well as between the GLS % and RWT among preeclamptic women. (N=50, r=0.3, P=0.03). Conclusion: the study concluded a significant correlation between GLS% with increasing in both PWT and RWT in preeclamptic women.

key word
Preeclampsia, echocardiography, global longitudinal strain, posterior wall thickness and relative wall thickness

References

  1. Shah, Silvi. “Hypertensive disorders in pregnancy.” Obstetric and Gynecologic Nephrology: Women’s Health Issues in the Patient with Kidney Disease (2020): 11-23.

  2. Agrawal, Akanksha, and Nanette K. Wenger. “Hypertension during pregnancy.” Current Hypertension Reports 22.9 (2020): 64.

  3. Karrar SA, Martingano DJ, Hong PL. Preeclampsia. [Updated 2024 Feb 25]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK570611/

  4. Tanner, Michael S., et al. “The evolution of the diagnostic criteria of preeclampsia-eclampsia.” American Journal of Obstetrics and Gynecology 226.2 (2022): S835-S843.

  5. Dionisio, Laura Mattana, and Giovani Marino Favero. “Platelet indices and angiogenesis markers in hypertensive disorders of pregnancy.” International Journal of Laboratory Hematology 46.2 (2024): 259-265.

  6. Kazma, Jamil M., et al. “Anatomical and physiological alterations of pregnancy.” Journal of Pharmacokinetics and Pharmacodynamics 47.4 (2020): 271-285.

  7. Zangeneh, Maryam, et al. “Electrocardiographic changes in healthy and preeclamptic pregnant women.” Journal of Kermanshah University of Medical Sciences 16.4 (2012): e78789.

  8. Lang, Roberto M., et al. “Recommendations for chamber quantification: a report from the American society of Echocardiography’s guidelines and standards committee and the chamber quantification writing group, developed in conjunction with the European association of Echocardiography, a branch of the European society of cardiology.” Journal of the American Society of Echocardiography 18.12 (2005): 1440-1463.

  9. Vlahović-Stipac, Alja, et al. “Left ventricular function in gestational hypertension: serial echocardiographic study.” American Journal of Hypertension 23.1 (2010): 85-91.

  10. Mostafavi, Atoosa, et al. “Comparison of left ventricular systolic function by 2D speckle-tracking echocardiography between normal pregnant women and pregnant women with preeclampsia.” Journal of Cardiovascular and Thoracic Research 11.4 (2019): 309.

  11. Al-Allak, Hanan Mohsen Ali, and Asaad Hasan Noaman Al-Aboodi. “A four-dimensional volumetric quantification of the left ventricle in healthy pregnant women in the third trimester.” Cureus 15.10 (2023): e46342.

  12. Hauge, Maria G., et al. “Left ventricular hypertrophy in women with a history of preeclampsia.” Hypertension (2024): https://doi.org/10.1161/HYPERTENSIONAHA.124.2349.

  13. Ajmi, H., et al. “Interest of speckle tracking in the detection of cardiac involvement in pregnant women with hypertensive disorder.” Pregnancy Hypertension 11 (2018): 136-141.

  14. De Haas, S., et al. “Cardiac remodeling in normotensive pregnancy and in pregnancy complicated by hypertension: systematic review and meta‐analysis.” Ultrasound in Obstetrics & Gynecology 50.6 (2017): 683-696.

  15. Cong, Juan, et al. “Quantitative evaluation of longitudinal strain in layer-specific myocardium in patients with preeclampsia.” The International Journal of Cardiovascular Imaging 34.2 (2018): 193-200.

  16. Buddeberg, B. S., et al. “Cardiac maladaptation in term pregnancies with preeclampsia.” Pregnancy Hypertension 13 (2018): 198-203.

  17. Urbano-Moral, Jose Angel, et al. “Investigation of global and regional myocardial mechanics with 3-dimensional speckle tracking echocardiography and relations to hypertrophy and fibrosis in hypertrophic cardiomyopathy.” Circulation: Cardiovascular Imaging 7.1 (2014): 11-19.

  18. Galderisi, Maurizio, et al. “Correlates of global area strain in native hypertensive patients: a three-dimensional speckle-tracking echocardiography study.” European Heart Journal–Cardiovascular Imaging 13.9 (2012): 730-738.”

Journal Help

Indexation

Scopus
ICV: 116.28
MNiSW: 20
Polish Medical Bibliography
Search all articles by
RCD Classification
User
Username:
Password:
Remember
Keywords
Classification of Rare Cardiovascular Diseases anticoagulation atrial fibrillation atrial septal defect cardiac tumor cardiomyopathy computed tomography congenital heart disease echocardiography electrocardiogram electrocardiography heart failure implantable cardioverter‑defibrillator magnetic resonance imaging pregnancy pulmonary arterial hypertension pulmonary hypertension rare cardiovascular disease rare disease right heart catheterization right ventricular failure
Journal Content
Search
Browse
Copyright © 2025 Journal of Rare Cardiovascular Diseases